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Breast cancer (BC) is one of the most complex, diverse and leading cause of death in women worldwide.The present investigation aims to explore genes panel associated with BC in different African regions, and compare them to those studied worldwide.
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Overall survival (n = 32) and progression-free survival (n = 30) were the most commonly reported efficacy outcomes. Targeted therapies, followed by chemotherapy in forms of combinations of 2 or more subclasses, composed most trials in TNBC, with immunotherapy being rarely used thus far.
The trials were mainly conducted in metastatic or advanced setting, followed by neoadjuvant and adjuvant settings.
Comparison across different TNBC treatment options warrants further investigation as the growing evidence base evolves.
The Commonwealth Department of Health commissioned Allen and Clarke Policy and Regulatory Specialists to prepare a literature review on breast density, to inform Breast Screen Australia’s position statement on breast density and screening.