Breast Cancer Literature Review

Breast Cancer Literature Review-45
Breast cancer (BC) is one of the most complex, diverse and leading cause of death in women worldwide.The present investigation aims to explore genes panel associated with BC in different African regions, and compare them to those studied worldwide.

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If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence ( which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

Overall survival (n = 32) and progression-free survival (n = 30) were the most commonly reported efficacy outcomes. Targeted therapies, followed by chemotherapy in forms of combinations of 2 or more subclasses, composed most trials in TNBC, with immunotherapy being rarely used thus far.

The trials were mainly conducted in metastatic or advanced setting, followed by neoadjuvant and adjuvant settings.

Comparison across different TNBC treatment options warrants further investigation as the growing evidence base evolves.

The Commonwealth Department of Health commissioned Allen and Clarke Policy and Regulatory Specialists to prepare a literature review on breast density, to inform Breast Screen Australia’s position statement on breast density and screening.


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